Doctor's Formulas D-Mannose for the urinary system 60.caps - Dietary Supplement, D-Mannose Formula

Formula D - Mannose is a dietary supplement containing the monosaccharide D-mannose.

What is D-Mannose?

D-mannose is a simple sugar, which has a special contribution to metabolism, through its role in the glycosylation of certain proteins. D-mannose is rapidly absorbed and reaches the peripheral organs in about 30 minutes and is then excreted by the urinary system. It cannot be converted to glycogen, therefore it is not stored in the body. It attaches to lectins and thus prevents the attachment of pathogens to the walls of the bladder.

Action mechanism

Its mechanism of action is expressed through inhibition of adhesion of the FimH surface protein. By direct binding of FimH to D-mannose bound to a vector protein, which is responsible for receptor specificity.

The first adhesion step involves the binding of mannose-sensitive FimH to the epithelium. The bladder wall is coated with various mannose-glycosylated proteins, such as Tamm-Horsfall protein (THP), which directly interferes with the adhesion of germs to the mucosa. Tamm-Horsfall protein (THF) can bind to E. coli with a specific bond, which can be inhibited by exogenous D-mannose.

By inhibiting the adhesion of germs to the urinary tract epithelium, D-mannose mimics the function of the urinary tract epithelial barrier.

EOF Notification Number: 47421 / 27-04-2018
(The Notification Number to the EOF is not a marketing authorization from the EOF)
WARNINGS:
• Do not exceed the recommended daily dose.
S / D should not be used as a substitute for a balanced diet.
• Keep out of the reach of small children.
• This product is not intended to prevent, treat or cure any human disease.
• Consult your doctor if you are pregnant, breast-feeding, taking medication or have any health problems.

COMPOSITION IN NUTRITIONS

PER DAILY DOSE

(1 to 2 capsules) D - Mannose 500 - 1000 mg
OTHER INGREDIENTS: magnesium stearate, gelatin, silicon dioxide.
(*) Does not contain preservatives, gluten, perfumes, sweeteners, etc.
Content
60 capsules

Dosage
1 to 2 capsules a day