Proven Health Benefits of Lactobacillus Sporogenes (Bacillus Coagulans) 

The intestinal flora is not a silent ecosystem because it carries various physiological and immunological functions. The impact of the gastrointestinal tract on brain functions and consequently on behavior, including anxiety, mood, cognitive function and pain regulation, has been recognized since the 19th century.

The intestinal-brain axis has been categorized as a homeostatic way of communication using neuronal, hormonal and immune pathways. In the gastrointestinal tract, which is an active member of this axis, there are about 100 trillion organisms, mainly anaerobes, forming the microbe, which exceeds 10 times the total number of cells present in the human body!

The intestinal flora plays a key role in the development and proper functioning of both the innate and the adaptive immune system.

Poor diet, exposure to antibiotics and infections can cause “dysbiosis”, a disorder of the coexistence between intestinal flora and host, which favors invasion and growth of pathogens at the expense of "good" bacteria that promote health within the digestive tract.

♦ Delivery of a high concentration of probiotics in the form of spores, allows almost 100% to survive through the stomach and germinate stem cells that will soon colonize one or more parts of the small intestine.

⇒ Bacillus Coagulans (Lactobacillus Sporogenes) is a probiotic strain resistant to heat and gastric acid. It is used to improve the immune system and to treat diarrhea and constipation. Bacillus Coagulans forms reproductive structures called spores. 

 Coagulans and other spore forming bacteria are protected in a unique way. Their coating consists by a form of a protein that allows them to survive in the stomach acids and to reach the small intestine, where they will germinate and multiply (Jurekka, 2012).

Researchers pointed out in 2012, in a review of the bibliography, that this probiotic strain reaches the stomach in the form of spores and is exposed to stomach accelerating action and acidic PH that causes the seed to coat, so that they absorb water, swell, and begin the germination process. 

How does it work?

Once they arrive in the duodenum, the seeds will germinate and multiply rapidly (Jurekka 2012).

• It is estimated that the average duration of time between oral consumption and vegetation lasts about 4-6 hours (Gandhi 1988).
• This alone is obviously not an important asset. Their advantage lies in their ability to germinate throughout the intestinal tract, which makes them to stand out from the number of probiotics.
• With a survival rate of 85% (meaning 85% of the initial material will reach the intestinal tract intact), it is the #1 among the probiotics, because it has the capacity to become metabolically active in the intestine.
• As soon as it reaches the small intestine, it produces left-handed L (+) lactic acid (Ong 2016), the form that is more easily metabolized by the body for the synthesis of glycogen.
• Colonization is transient and its seeds are slowly excreted through the stools in about seven days after discontinuation (Majeed, 1998).

Lactobacillus Sporogenes (Bacillus Coagulans), as it passes through the digestive system, "contributes to a change in the intestinal environment, to support all of the intestinal flora" (Jurinka 2012). 

For example, in pigs that are the best animal model for the human digestive system, seed probiotics have been shown to reduce "bad" bacteria as effectively as antibiotics (Adami 1999). The important thing is that this is done without any negative effects on any of the "good bacteria" which makes them ideal for cases of chronic antibiotic administration (Zhenya 2015). 

How can these spore-forming bacteria improve the entire gastrointestinal microeconomics?

• By replenishing the amount of desirable microorganisms that will compete with pathogenic microbes
• By increasing the production of bacteriocins (substances that act as natural antibiotics)
• By increasing the production of short chain fatty acids that feed the intestinal mucosa 

Additionally, the direct influence on local and systemic inflammation observed in vitro and in vivo, explains the repeatedly observed positive effects of Lactobacillus Sporogenes (Bacillus Coagulans) on gastrointestinal disorders (local inflammation) and on metabolic & inflammatory problems such as arthritis. 

Furthemore enhances digestion of lactose because it has in vitro [beta] -galactosidase activity and may also have lactate dehydrogenase activity, thereby enhancing the absorption of lactose for those intolerant to it (Jurinka 2012). 

Also improves the cholesterol profile because of its effectiveness in modifying lipid metabolism through bile hydrolase, which has a direct effect on the metabolism of bile salts of the host. Cholesterol-lowering properties occur because they can assimilate and integrate the cellular structure of cholesterol by blocking cholesterol in the intestine and inhibiting the enzyme HMG-CoA reductase responsible for cholesterol production (Mohan 1990). 

In which cases, the administration of this type of beneficial Spore-Foaming and Lactic-Acid producing bacteria, is recommended?

Promoting a healthy and balanced intestinal flora, with all the associated benefits for the body, is recommended, especially after antibiotic treatments and in the elderly, because the prevalence of "good" bacteria is decreasing over time (Nyan gale in 2015).

However, due to its advantages, B. Coagulans (Lactobacillus Sporogenes) can act as a preventative, but also to heal "dysbiosis" (i.e. the excessive growth of pathogenic microorganisms).

Other studies have suggested that enzyme supplements could have immunomodulatory activity and might be useful in preventing or treating autoimmune diseases. 

Research has shown that this powerful probiotic strain can help:

1. in the fight against Irritable Bowel Syndrome (IBS),
2. by averting conditions in Crohn’s Disease
3. by preventing diarrhea, associated with antibiotics (Dutta 2011),
4. in the flatness, bloating and gas (Kalman 2009),
5. by improving hyperlipidemia,
6. in immunomodulatory activity by preventing or treating autoimmune diseases, such as osteoarthritis, rheumatoid arthritis, e.t.
7. but also help the body cope with viral attacks, such as influenza (Baron 2009).
8. It can enhance athletic performance because it has the ability to reduce muscle damage markers, increase recovery, and maintain athletic performance after muscle damage in exercise (Jäger 2015).
9. For women's health when administered topically, it has been shown to be an alternative for women suffering from non-specific vaginosis (Shirodkar 1980.)