Ricerfarma Gengigel baby Teething gingival gel 20ml - For the first teeth of your baby

As the infant's teeth come out the first time cause inflammation and pain which is treated with the topical gel Gengigel.

Contains no sugar, preservatives and dyes and alcohol.

Contains Hyaluronic acid 

It does not cause irritation if swallowed.

• Hyaluronic acid (hyaluronan) is an indispensable component of intact, healthy gums and oral mucosal tissue. 
  It is distributed in a selective, specific manner and tends to concentrate particularly in those layers of the gingival 
  epithelium closest to the surface, where it acts as a barrier imparting stability and elasticity to the periodontal 
  connective tissue.
• • As hyaluronic acid (hyaluronan) is a purely physiological substance devoid of any toxic or unpleasant accompanying 
    phenomena, it can be used without restriction by children, pregnant women, diabetics, vegetarians and the elderly. 
    In the case of inflammations and injuries, for example, hyaluronic acid is broken down and dissolved by the enzyme 
    hyaluronidase. If oral hygiene is poor, hyaluronidase is produced and released by bacterial plaque.
  • • The enzyme induces a loosening of the structure and a slackening of the tissue and facilitates fluid exchange between 
      the tissue and the vascular system, causing mild oedemas to form. 
      The enzymatic breakdown (catabolisation) of hyaluronic acid by hyaluronidase significantly increases the permeability 
      of tissue and capillaries with the consequence that toxins, drugs and bacteria can propagate more easily. 
      This in turn leads, amongst other things, to poor healing and tissue inflammation.
    • The Action
      By normalising the natural cohesive structure of the connective tissue (macro-aggregation of the proteoglycans), 
      hyaluronic acid accelerates the rate of tissue reconstruction. The weakening of the mucosal tissue due to the influence
      of bacterial hyaluronidase is thus reduced. A further biological function of hyaluronic acid in tissue regeneration is its 
      ability to influence both the migration of fibroblasts and fibrogenesis, with the result that scar tissue formation and 
      wound healing are promoted.
    • • Hyaluronic acid possesses an extremely high capacity to bind water (up to 200 times its own volume); thanks to this 
        property, HA produces an anti-oedematous effect. The molecular structure of hyaluronic acid or, more exactly, the 
        molecular chains formed by the glycosaminoglycans, binds not only water, but also specific proteins and their tissue 
        polysaccharides, by means of hydrogen bond bridges, to form a viscous macro-aggregate.
      • • Hyaluronic acid combats the inflammation caused by hyaluronidase-producing bacteria by inactivating the enzyme. 
          Hyaluronic acid regulates cell permeability and reduces abnormally high capillary permeability. 
          This helps to prevent infestation by infectious micro-organisms, thus inhibiting tissue destruction. (source : Ricerfarma.com)